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Results in APCAT for SNPs at loci with strong previously published evidence of association with asthma.

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Figshare2012-09-28 更新2026-04-29 收录
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aGene shown is nearest gene to associated SNP. SNPs from the same locus are grouped together. bReferences: 1 = Moffatt et al. (2010) [17]; 2 = Moffatt et al. (2007) [7]; 3 = Gudbjartsson et al. (2009) [16]; 4 = Sleiman et al (2010) [13]; 5 = Himes et al (2009) [12]; 6 = Li et al. (2010) [22]. cAlleles are indexed to the forward strand of NCBI build36. dAPCAT P values are one-tailed with respect to the direction of the original association. eP values are from fixed-effect inverse-variance model of meta analysis. fResults shown are from Moffatt et al (2010), which is the larger and more recent study. g SNP rs9273349 is present in NFBC1966 data set only. hResults exclude the Framingham Heart Study, which contributed to the original report in Himes et al (2009) IShown here are the random effects P value in Gabriel data, the P value for fixed effects model had a genome wide significance P value of 1.4E-08 with no evidence of heterogeneity.
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2012-09-28
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