Urine phase preferring protein list.

The 7 proteins from the list of the top 60 most highly abundant and highly prevalent proteins in CaOx stone matrix (from Table 2 in [Reference 8]) that demonstrated higher abundance in urine than CaOx stone matrix, including UROM (uromodulin), EGF (epidermal growth factor), APOD (apolipoprotein D), ALBU (albumin), IGKC (Ig kappa chain C region), IGHG1 (Ig gamma-2 chain C) and IPSP (plasma serine protease inhibitor), were added to the 31 proteins found in stone former urine at high relative abundance (>0.5%) but not in the list of the top 60 proteins from CaOx stone matrix in SFU samples (see Supplementary Data Table S6 in [Reference 21] and Table 2 from [Reference 8]) to create the list of 38 urine preferring proteins in this table. The abbreviations, accession numbers, and protein names are given for each protein, as well as the number of aspartate (D), glutamate (E), arginine (R), and lysine (K) residues in each protein, listed as both absolute totals and percentages for each amino acid. Total charge and net charge were calculated for each protein as described in the Methods section, and each was listed as both absolute totals and percentages for these 38 proteins. A column containing the updated accession number for 1 protein which had changed from the original publication has been added. (XLSX)