Mast cell tolerance in the skin microenvironment to commensal bacteria is controlled by fibroblasts [single-cell RNA-seq]

To investigate the cooperative function of dermal fibroblast and mast cell in inducing mast cell tolerance to commensals We then performed gene expression profiling analysis using data obtained from SC RNA seq of mast cells, dermal fibroblast and and mast cells in co culture with dermal fibroblasts . Comparative gene expression profiling analysis of single cell RNA-seq data for conditioned and not conditioned mast cells