E-GEOD-50693

NIAID Data Ecosystem2026-05-02 收录

乳腺癌他莫昔芬耐药

浸润性小叶癌内分泌治疗

数据链接：

https://www.omicsdi.org/dataset/atlas-experiments/E-GEOD-50693 数据链接链接失效反馈

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资源简介：

Endocrine response in invasive lobular carcinoma is characterized by unique estrogen-mediated gene expression and de novo tamoxifen resistance (MM134)

创建时间：

2025-01-24

RNA-sequencing and MeDIP-sequencing of shSRC-1 and shNT tamoxifen treated LY2 cells. RNA-sequencing and MeDIP-sequencing of shSRC-1 and shNT tamoxifen treated LY2 cells

乳腺癌他莫昔芬耐药

甲基化与转录组关联分析

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

NIAID Data Ecosystem80

Tamoxifen-resistant human breast cancer cell lines

乳腺癌他莫昔芬耐药

耐药基因表达谱

A functional genetic screen to identify genes causing tamoxifen resistance in an estrogen-dependent human breast cancer cell model was performed. By insertion of defective retrovirus into the genome,

NIAID Data Ecosystem50

Over-expressed genes in chromosomal regions 17q12, 17q21.33-q25.1, 8p11.2 and 8q24.3 associated with early relapse in ER+ breast cancers treated with tamoxifen.

乳腺癌他莫昔芬耐药

早期复发基因标志物

List of genes associated with early relapse on chromosomes 8 and 17. Highlighted in bold are cancer related genes of interest.

NIAID Data Ecosystem30

An H3K4me3 reader, BAP18 as an adaptor of COMPASS-like core subunits co-activates ERa action to confer to tamoxifen resistance in breast cancer

乳腺癌他莫昔芬耐药

表观遗传调控

Estrogen receptor alpha (ERalpha signaling pathway is essential for ERalpha positive breast cancer progression and endocrine therapy resistance. BPTF associated protein of 18kDa (BAP18) has been recog

NIAID Data Ecosystem60

Inflammatory cytokines activate unliganded estrogen receptor and alter the sensitivity of breast cancer cells to tamoxifen. Homo sapiens

乳腺癌他莫昔芬耐药

炎症-雌激素信号串扰

Genome-wide analyses of the transcriptomes and transcription factor recruitment in estrogen receptor breast cancer cells in response to estradiol, IL1b, or TNFa treatments. Also, the role of inflammat

NIAID Data Ecosystem40

E-GEOD-50693

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