Co-evolution of Met amplification and Hgf overexpression mediate resistance to BRAF inactivation in mouse anaplastic thyroid cancers.
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE118022
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Affymetric arrays were performed on thyroid samples collected from GEMMs: normal thyroid, TPO-Cre/LSL-Braf (PTC), TPO-Cre/tetO-BRAF/LSL-rtTAiresGFP/p53-flox (ATC) and TPO-Cre/tetO-BRAF/LSL-rtTAiresGFP/p53-flox (recurrent tumors) As above Thyroids and tumor-bearing thyroid glands were isolated from various mouse models at baseline
创建时间：
2018-11-01
