File S1 - Adaptation of a Cyanobacterium to a Biochemically Rich Environment in Experimental Evolution as an Initial Step toward a Chloroplast-Like State

Supporting information which contains the following. Figure S1: Toxic components in TCM1. Figure S2: Preculture for the evolution experiment. Figure S3: The specific growth rates as a function of the relative concentration of the toxic amino acids in each transfer round. Figure S4: Population dynamics in the evolution experiment. Figure S5: The difference between the approximate analytical solution (Equation 2) and the numerical simulation according to Equation 1. Table S1: Components of TCM1. Table S2: All detected mutations in the chromosome, relative to the reference (NC_000911.1; Synechocystis sp. PCC 6803 chromosome, complete genome), by the genomic analysis. Text S1: The derivation of Equations 1 and 2. Appendix S1: The Matlab source code of the simulation shown in Figure 3A-i (blue bold line). (PDF)