Summary of primary and secondary endpoints for patients infected with nalidixic acid-resistant isolates of <i>S.</i> Typhi and <i>S</i>. Paratyphi A (primary analysis population).

$Patients may have more than one type of treatment failure. Kaplan-Meier estimates. HR = Hazard ratio (based on Cox regression), RD = absolute risk difference (based on Kaplan-Meier estimates), CI = 95% confidence interval interval, IQR = inter-quartile range. n number of patients; pt patients. #Footnote: If persistent fever on day 7 (instead of day 10) would already be considered a treatment failure event (“modified analysis”), then there would be 21 treatment failures in the ofloxacin group vs. 11 in the gatifloxacin group (with 16 vs. 7 patients with persistent fever on day 7): HR = 0.46 (CI 0.22–0.96), p = 0.04.