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Base-Promoted Synthesis of Quinoline-4(1H)‑thiones from o‑Alkynylanilines and Aroyl Isothiocyanates

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Figshare2017-11-01 更新2026-04-29 收录
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https://figshare.com/articles/dataset/Base-Promoted_Synthesis_of_Quinoline-4_1_i_H_i_thiones_from_i_o_i_Alkynylanilines_and_Aroyl_Isothiocyanates/5558845
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A base-promoted synthesis of quinoline-4­(1H)-thiones has been accomplished from the in situ generated o-alkynylthiourea, obtained by reacting o-alkynylanilines with aroyl/acyl isothiocyanates. A 6-exo-dig S-cyclization of the in situ generated thiourea is followed by a rearrangement to give quinoline-4­(1H)-thiones.
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2017-11-01
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