CamA Adenine Methyltransferase Complexed to Cognate Substrate DNA and Inhibitor SGC8158
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CamA Adenine Methyltransferase Complexed to Cognate Substrate DNA and Inhibitor SGC8158 Descriptor: 1,2-ETHANEDIOL, 5'-S-(4-{[(4'-chloro[1,1'-biphenyl]-3-yl)methyl]amino}butyl)-5'-thioadenosine, DNA Strand 1, ... Authors: Horton, J.R, Cheng, X, Zhou, J. Deposit date: 2021-07-14 Release date: 2021-09-15 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Repurposing epigenetic inhibitors to target the Clostridioides difficile- specific DNA adenine methyltransferase and sporulation regulator CamA. Epigenetics, 17, 2022
数据集名称:与同源底物DNA及抑制剂SGC8158结合的CamA腺嘌呤甲基转移酶复合物 成分描述:1,2-乙二醇、5'-S-(4-{[(4'-氯代[1,1'-联苯]-3-基)甲基]氨基}丁基)-5'-硫代腺苷、DNA链1等 作者:Horton, J.R.、Cheng, X.、Zhou, J. 存储日期:2021-07-14 发布日期:2021-09-15 最后修改日期:2023-10-18 实验方法:X射线衍射(X-RAY DIFFRACTION,分辨率2.5 Å) 引用文献:《重新利用表观遗传抑制剂靶向艰难梭菌特异性DNA腺嘌呤甲基转移酶及孢子形成调节因子CamA》,《表观遗传学》(Epigenetics),2022年,第17卷



