Genome-wide DNA methylation pattern in whole blood associated with primary intracerebral hemorrhage

To reveal the role of DNA methylation in peripheral blood from primary intracerebral hemorrhage(ICH) ,DNAs from 30 ICH patients and 34 matched controls were analyzed by methylation microarray. In total, we identified 1377 hypomethylated and 153 hypermethylated differentially methylated positions (DMPs) in peripheral blood from ICH patients compared to healthy controls. Peripheral blood samples from 30 patients with ICH and 34 matched controls were analyzed by Illumina Infinium HumanMethylation850K BeadChip.