Summary of amino acid mutations found in the HA protein of CVI P42, and their locations in respect to antigenically-relevant regions.

Amino acid numbers are shown according to A/turkey/Turkey/1/05 (H5N1) and the reference strain A/goose/Guangdong/1/96 (H5N1) numbering (the latter numbering is used throughout the report unless stated otherwise). Mutations found in common between CVI and FLI isolates are shown in bold. The locations of amino acid substitutions in respect to antigenically relevant regions – according to Duvvuri, et al., (2009) – are shown in the last column (where available). AS: Antigenic Site; PS Site: Positive Selection Site; AP: Antigenic Peptide; RBS: Receptor Binding Site; NA: Not Assigned a function.