Transport of L1 into endosomes

Membrane bound L1 is internalized through clathrin coated vesicles and is endocytosed into recycling endosomes. Moreover, L1 promotes co-endocytosis of beta1 integrins with which it is associated into early endosomes.

膜结合的L1通过有包被的笼形囊泡被内化，并被摄取至回收的早期内体中。此外，L1促进与其相关的beta1整合素与自身一同被摄取至早期内体中。