Crystal structure of profragilysin-3 (proBFT-3) from Bacteroides fragilis in complex with flumequine

Crystal structure of profragilysin-3 (proBFT-3) from Bacteroides fragilis in complex with flumequine Descriptor: (12~{R})-7-fluoranyl-12-methyl-4-oxidanylidene-1-azatricyclo[7.3.1.0^{5,13}]trideca-2,5(13),6,8-tetraene-3-carboxylic acid, BFT-3, CHLORIDE ION, ... Authors: Eckhard, U, Guevara, T, Gomis-Ruth, F.X. Deposit date: 2021-09-09 Release date: 2022-09-14 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Repositioning small molecule drugs as allosteric inhibitors of the BFT-3 toxin from enterotoxigenic Bacteroides fragilis. Protein Sci., 31, 2022

本数据集为来自脆弱拟杆菌（Bacteroides fragilis）的前脆弱溶素-3（proBFT-3）与氟甲喹（flumequine）形成复合物的晶体结构。
描述项：(12R)-7-氟-12-甲基-4-氧代-1-氮杂三环[7.3.1.0^{5,13}]十三碳-2,5(13),6,8-四烯-3-羧酸、BFT-3、氯离子（CHLORIDE ION）等。
作者：Eckhard U、Guevara T、Gomis-Ruth F.X.
存档日期：2021-09-09
发布日期：2022-09-14
最后修改日期：2024-01-31
实验方法：X射线衍射（X-RAY DIFFRACTION），分辨率1.95埃（Å）
引用文献：Repositioning small molecule drugs as allosteric inhibitors of the BFT-3 toxin from enterotoxigenic Bacteroides fragilis. Protein Sci., 31, 2022，即《将小分子药物重新定位为产肠毒素脆弱拟杆菌BFT-3毒素的变构抑制剂》，发表于《Protein Science》2022年第31卷。