five

RNA-seq Analysis of sibling and dhx38-- zebrafish

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NIAID Data Ecosystem2026-03-13 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE165203
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Purpose: Loss of dhx38 disrupts the proliferation and differentiation balance of hematopoiesis. Notably, the mitosis of both EMPs and HSPCs are blocked in the pre-metaphase with abnormal chromatin karyotype in the dhx38--zebrafish. RNA-seq analysis screened abnormal splicing and aberrant expression genes that are likely to explain the dysfunction of mitosis. Tail tissue mRNA profiles of 36 hpf sibling (WT) and dhx38--zebrafish
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2022-08-09
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