five

epigenetic control of neurogenesis-to-gliogenesis switch during mouse cortical development

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE234101
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Gene expression and chromatin accessiblity changes as cortical RG switch from neurogenesis to gliogenesis; the bivalent chromatin present in the temporally upregulated genes maintain them poised. ATAC-seq of P1 hGFAP-GFP FASC isolated cells, cut&tag of H3K4me3 and H3K27me3 to identfy the bivalent chromatin during cortical development
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2023-06-10
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