HTP

The HepatoToxicity Portal (HTP) is a publicly accessible platform that integrates a curated knowledgebase (HTP-KB) and a machine learning-based prediction model (HTP-Pred) to assess liver toxicity. It consolidates hepatotoxicity data from nine major databases, offering valuable resources for drug development with an intuitive interface and advanced predictive capabilities.

肝毒性门户（HepatoToxicity Portal, HTP）是一款公开可访问的平台，整合了精选知识库（curated knowledgebase, HTP-KB）与基于机器学习的预测模型（machine learning-based prediction model, HTP-Pred），用于肝毒性评估。该平台汇集了九大主流数据库的肝毒性数据，凭借直观的交互界面与先进的预测能力，为药物研发提供了宝贵的研究资源。

搜集汇总

背景与挑战

背景概述

HTP是一个专注于小分子肝毒性的综合资源门户，整合了9个公共资源的化学毒性数据，并提供基于化学结构和基因表达谱的肝毒性预测工具。