Expression data from DD neurons isolated from early L1 stage C. elegans larvae.

Six DD class GABAergic neurons are generated in the embryo to synapse with ventral muscles and receive input from cholinergic neurons in the dorsal nerve cord. After hatching and toward the end of the first larval (L1) stage, DD neurons reverse polarity (i.e., synapse with dorsal muscles, receive ventral cholinergic inputs). Expression profiles were generated from DD neurons in the early L1 stage before the initiation of the remodeling program. We used microarray analysis to detect transcripts with potential roles in DD remodeling.本数据集涉及的6种DD类γ-氨基丁酸能（GABAergic）神经元，于胚胎发育阶段产生，可与腹部肌肉形成突触，并接收背神经索内胆碱能神经元的信号输入。在孵化完成并进入第一幼虫期（L1）末期时，DD神经元会发生极性反转，即转而与背部肌肉形成突触，并接收腹部胆碱能神经元的信号输入。研究人员在该神经元重塑程序启动前，采集了早期L1阶段DD神经元的表达谱数据。本研究采用微阵列（microarray）分析技术，筛选出在DD神经元重塑过程中潜在发挥功能的转录本。