Gut microbiota mediated the progress of Tuberculosis. Gut microbiota mediated the occurrence and drug resistance development of Tuberculosis

Tuberculosis is now the second leading cause of death of infectious diseases after COVID-19. The emergence of MDR-TB has made treatment more difficult. However, the disease mechanisms of tuberculosis and drug-resistant diseases related to the gut microbiota are still not clear.Here, we research on the microbiome’s association with Drug-resistant tuberculosis. The models using α diversity, differential bacteria and differential pathways as predictors showed high accuracy and reliability in predicting the The occurrence of tuberculosis and the occurrence of drug-resistant tuberculosis.