Characteristics and allele frequencies of the chemokine receptor variants.

1Chromosome position is based on the NCBI genome build 36.3;2TM, Transmembrane domain; ECL, extracellular loop;3Variant allele frequency (freq.) was obtained from participants in AIDS cohorts consisting of European American (EA) and African American (AA);4Synonymous nucleotide T/C change at position 255 in the GenBank sequence U51241;5Nucleotide G/A change at 2459 bp upstream of CCR5 ORF.