Data_Sheet_1_Waist-to-height ratio and new-onset hypertension in middle-aged and older adult females from 2011 to 2015: A 4-year follow-up retrospective cohort study from the China Health and Retirement Longitudinal Study.docx

BackgroundCentral obesity was closely associated with hypertension. Middle-aged and older adult females, defined as those aged 45 and above, were more likely to suffer from central obesity. For waist-to-height ratio (WHtR) was used as central obesity assessment, the object of this study was to illustrate the relationship between WHtR and the incidence of hypertension in middle-aged and older adult females in China.MethodsData used in this prospective cohort study was derived from the China Health and Retirement Longitudinal Study (CHARLS) in a baseline survey from 2011 to 2012 with a follow-up duration of 4 years. The waist-to-height ratio was calculated as waist circumstance divided by height, and the cohort was divided into different groups based on WHtR level. The outcome variable was new-onset hypertension.ResultsOf the 2,438 participants included in the study, 1,821 (74.7%) had high WHtR levels (WHtR ≥ 0.5). As WHtR was closely related to new-onset hypertension in a multivariable logistics regression mode [OR: 7.89 (95% CI: 2.10–29.67)], individuals with high WHtR were also more likely to suffer from hypertension compared with low WHtR levels [OR: 1.34 (95% CI: 1.06–1.69)].ConclusionWHtR is positively related to the risk of hypertension incidents among middle-aged and older adult females. Individuals with WHtR ≥ 0.5 were more likely to suffer from hypertension.

背景中心性肥胖与高血压密切相关。中年及老年女性，即45岁及以上的女性，更容易遭受中心性肥胖的困扰。本研究旨在阐述腰高比（WHtR）与我国中年及老年女性高血压发病率之间的关系。方法本研究采用前瞻性队列研究方法，数据来源于2011年至2012年的中国健康与养老追踪调查（CHARLS）基线调查，随访时间为4年。腰高比通过腰围与身高的比值计算得出，并根据WHtR水平将队列分为不同的组别。结果变量为新发高血压。在2,438名研究对象中，1,821人（74.7%）的WHtR水平较高（WHtR ≥ 0.5）。在多变量逻辑回归模型中，WHtR与高血压新发病例密切相关[OR: 7.89 (95% CI: 2.10–29.67)]，与低WHtR水平相比，WHtR ≥ 0.5的个体更易患高血压[OR: 1.34 (95% CI: 1.06–1.69)]。结论腰高比与中年及老年女性高血压发病风险呈正相关。WHtR ≥ 0.5的个体更易遭受高血压的侵袭。