IVIS analysis of <i>in vivo</i> antimicrobial activity of ARD peptide against K. pneumoniae.

(A) K. pneumoniae-infected mice were treated with either PBS (n = 5) or 10 mg/kg ARD peptide (n = 5) at 1 hour post-inoculation. Four hours post-inoculation, mice were anesthetized and imaged. Bacterial load was displayed in the photographic image with an overlay of bioluminescence. False color imaging represents intense luminescence in red, moderate luminescence in green and low luminescence in blue and purple. (B) Total flux was quantified by IVIS imaging software. **P<0.01 (Mann-Whitney U test) for PBS and ARD peptide HBc147-183.