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Transcriptome analysis in the mouse migratory PGCs

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NIAID Data Ecosystem2026-03-11 收录
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Primordial germ cells (PGCs), the founder cells of the germline, are specified in pre-gastrulating embryos in mammals, and subsequently migrate towards gonads to mature into functional gametes. We profile the transcriptome of mouse PGCs in migratory stage (at E10.5), to reveal enrichment of distinct gene sets at each transition point (by comparing with mouse gonadal PGCs or postnatal gametes: accession nos. DRA003597 and DRA006633), thereby providing an accurate transcriptional time-line for mouse PGC development.

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2020-01-10
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