Research data supporting "The ALS/FTD-related C9orf72 hexanucleotide repeat expansion forms RNA condensates through multimolecular G-quadruplexes"

Data repository for work contributing to the paper "The ALS/FTD-related C9orf72 hexanucleotide repeat expansion forms RNA condensates through multimolecular G-quadruplexes". Confocal micrographs are presented as raw .TIFF files with corresponding metadata .txt file, which can be opened using text editing software such as Notepad. Confocal micrographs were collected using a Leica SP8 Inverted Confocal microscope (HC PL APO CS2 10x/0.40 DRY | HC PL APO CS2 20x/0.75 DRY objectives). Circular Dichroism spectra were collected using a Quartz High Precision cell (1 mm light path) and analysed in the Jasco J-715 Spectropolarimeter. The RAW data is saved in .xlsx file which can be accessed in Microsoft Excel or any other txt reader. Gel imaging was performed with Typhoon FLA 9500. The images are saved in a .ppt file which can be opened with Microsoft Powerpoint. Flow Cythometry data was aquired using a BD LSRFortessa analyser operated by the FACSDiva software (BD), and the results were analysed using the FlowJo software. The paper is open access and further details for the data acquisition can be found in the Methods section.