Crystal Structure of human FABP5 in complex with (1S,2R)-2-[(5-carbamoyl-3-ethoxycarbonyl-4-methyl-2-thienyl)carbamoyl]cyclohexanecarboxylic acid

Crystal Structure of human FABP5 in complex with (1S,2R)-2-[(5-carbamoyl-3-ethoxycarbonyl-4-methyl-2-thienyl)carbamoyl]cyclohexanecarboxylic acid Descriptor: (1R,2S)-2-{[5-carbamoyl-3-(ethoxycarbonyl)-4-methylthiophen-2-yl]carbamoyl}cyclohexane-1-carboxylic acid, DIMETHYL SULFOXIDE, Fatty acid-binding protein 5, ... Authors: Ehler, A, Benz, J, Obst, U, Rudolph, M.G. Deposit date: 2023-04-27 Release date: 2023-06-14 Last modified: 2025-08-13 Method: X-RAY DIFFRACTION (1.24 Å) Cite: A high-resolution data set of fatty acid-binding protein structures. III. Unexpectedly high occurrence of wrong ligands. Acta Crystallogr D Struct Biol, 81, 2025

人源脂肪酸结合蛋白5（Fatty acid-binding protein 5, FABP5）与(1S,2R)-2-[(5-氨基甲酰基-3-乙氧羰基-4-甲基-2-噻吩基)氨基甲酰基]环己烷羧酸的共晶晶体结构。配体描述：(1R,2S)-2-{[5-氨基甲酰基-3-(乙氧羰基)-4-甲基噻吩-2-基]氨基甲酰基}环己烷-1-羧酸、二甲基亚砜（DIMETHYL SULFOXIDE）、脂肪酸结合蛋白5等。作者：Ehler, A、Benz, J、Obst, U、Rudolph, M.G.。沉积日期：2023-04-27；发布日期：2023-06-14；最后修改日期：2025-08-13。实验方法：X射线衍射（X-RAY DIFFRACTION），分辨率1.24埃（Å）。引用文献：《脂肪酸结合蛋白结构高分辨率数据集 Ⅲ. 错误配体的意外高发生率》，发表于《Acta Crystallogr D Struct Biol》，第81卷，2025年。