Crystal Structure of full-length Human Lysyl Hydroxylase LH3 - Val80Lys mutant - Cocrystal with Fe2+, Mn2+, UDP-Glucose
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Crystal Structure of full-length Human Lysyl Hydroxylase LH3 - Val80Lys mutant - Cocrystal with Fe2+, Mn2+, UDP-Glucose Descriptor: 2-OXOGLUTARIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Chiapparino, A, De Giorgi, F, Scietti, L, Faravelli, S, Roscioli, T, Forneris, F. Deposit date: 2019-11-12 Release date: 2021-05-19 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Identification of Regulatory Molecular 'Hot Spots' for LH/PLOD Collagen Glycosyltransferase Activity Int J Mol Sci, 2023
全长人类赖氨酰羟化酶LH3(Lysyl Hydroxylase LH3)Val80Lys突变体的晶体结构——与Fe²+、Mn²+及UDP-葡萄糖(UDP-Glucose)共结晶复合物。配体组成:2-氧代戊二酸、2-乙酰胺基-2-脱氧-β-D-吡喃葡萄糖、2-乙酰胺基-2-脱氧-β-D-吡喃葡萄糖-(1→4)-2-乙酰胺基-2-脱氧-β-D-吡喃葡萄糖等。作者:Chiapparino A、De Giorgi F、Scietti L、Faravelli S、Roscioli T、Forneris F。提交日期:2019年11月12日;发布日期:2021年5月19日;最后修改日期:2024年11月20日。实验方法:X射线衍射(X-RAY DIFFRACTION),分辨率2.3 Å。引用文献:《调控LH/PLOD胶原蛋白糖基转移酶活性的分子“热点”区域鉴定》,《国际分子科学杂志(Int J Mol Sci)》,2023年。
创建时间:
2019-11-12



