Supplementary material of the project "Phylogenomics and chromosome mapping show that ectopic recombination of subtelomeres is critical for antigenic diversity and has a complex evolutionary history in <i>Plasmodium</i> parasites"
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<b>Supplementary material datasets:</b><b>Dataset 1:</b> Database for phylogenetic reconstruction of the genus <i>Plasmodium.</i><b>Dataset 2:</b> Trees of the genus <i>Plasmodium</i> generated with six phylogenetic tools. The four trees generated after removing the third base of codons in the alignments and the final majority-rule consensus tree of the ten trees are also included.<b>Dataset 3:</b> Database for chromosome mapping of gene conservation.<b>Dataset 4:</b> List of predominant gene families in young regions per species.<b>Dataset 5: </b>Classification of gene families (with the highest number of sequences in young regions) based on the nature of its products.<b>Dataset 6: </b>Chromosome maps showing the gene conservation profile, presence of young regions, and distribution of antigenic genes in 19 <i>Plasmodium</i> species.<b>Dataset 7: </b>A hundred comparisons of genomic features associated with the process of generating antigenic diversity through ectopic recombination of subtelomeres among equally sized subsamples (n=4) randomly generated from <i>Plasmodium</i>, <i>Laverania</i>, and <i>Vinckeia</i>. For the subgenus <i>Plasmodium</i>, the monophyletic subclade was included in the comparisons.<b>Supplementary material:</b><b>Table S1: </b>Number of species present in each major clade and in their respective minor clades.<b>Table S2:</b> Criteria to define the four levels in which <i>Plasmodium</i> species are classified based on evidence of the intensity of production of antigenic diversity through ectopic recombination.<b>Table S3: </b>Results of normality tests. Shapiro Wilk's test was used due to the small sample size per group (n<30). The statistic and p-value are shown.<b>Table S4: </b>Results of homoscedasticity tests. Levene's Test was applied to evaluate homoscedasticity when the data did not follow a normal distribution before conducting the Wilcoxon's test. The statistic and p-value are shown per test.<b>Table S5: </b>Results of Welch's and Wilcoxon's tests. When the data followed a normal distribution, Welch's test was used. Otherwise, Wilcoxon's test was applied after verifying homoscedasticity. The statistic and p-value are shown per comparison.<b>Figure S1:</b> Phylogenetic reconstruction of the genus <i>Plasmodium</i> after removing the third base of the codons in the alignments.<b>Figure S2:</b> Proportion of species-specific or young genes excluded from chromosome mapping analysis.<br>



