MOESM10 of Characterization of nAChRs in Nematostella vectensis supports neuronal and non-neuronal roles in the cnidarianâ bilaterian common ancestor

Additional file 10: Table S3. Edited amino acid alignment consisting of transmembrane domains and double cysteines necessary for acetylcholine binding. A protein alignment of confirmed bilaterian muscarinic and nicotinic acetylcholine receptors, GABAergic receptors, a confirmed Hydra muscarinic acetylcholine receptor, a potential N. vectensis nicotinic acetylcholine receptor and a cnidarian nicotinic acetylcholine receptor. Protein sequences were edited to consist of the four conserved transmembrane domains (TM1â TM4) and the double cysteines necessary for acetylcholine binding (denoted by asterisks).