Diastereoselective Fluorocyclopropanation of Chiral Allylic Alcohols Using an α‑Fluoroiodo­methylzinc Carbenoid

Chiral fluorocyclopropyl
carbinols were synthesized in high diastereoselectivities
via a zinc mediated cyclopropanation reaction, using sec-allylic alcohols as simple building blocks. An enantioselective
version of this transformation was achieved through in situ formation of chiral allylic zinc sec-alkoxides
from the requisite aldehydes using Walsh’s protocol.