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Targeting FOXA1-mediated repression of TGF-β signaling suppresses castration-resistant prostate cancer progression [microarray]

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NIAID Data Ecosystem2026-03-10 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE119758
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资源简介:
our study establishes FOXA1 as an important regulator of lineage plasticity mediated in part by TGF-β signaling and supports a novel therapeutic strategy to control lineage switching and potentially extend clinical response to antiandrogen therapies. Microarray analysis on LNRII cells with control and TGFB3. Microarray analysis on LNCaP cells with control and FOXA1 knockdown followed by LY2157299 treatment
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2018-12-06
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