Co-crystal structure of human 8-oxoguanine glycosylase N149C mutant with DNA containing photocaged 8-oxoguanine
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Co-crystal structure of human 8-oxoguanine glycosylase N149C mutant with DNA containing photocaged 8-oxoguanine Descriptor: CALCIUM ION, DNA (5'-D(*AP*(8OG)P*GP*TP*CP*TP*AP*C)-3'), DNA (5'-D(P*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*G)-3'), ... Authors: Imura, T, Yang, K.-C, Hosokawa, Y, Shih, H.-Y, Ban, Y, Yamamoto, J, Maestre-Reyna, M. Deposit date: 2024-11-14 Release date: 2025-07-23 Last modified: 2025-09-10 Method: X-RAY DIFFRACTION (2.81 Å) Cite: Revisiting the co-crystal structure of a DNA glycosylase with photocaged substrate: a suitable time-resolved crystallography target? Iucrj, 12, 2025
人类8-氧鸟嘌呤糖苷酶(8-oxoguanine glycosylase)N149C突变体与含光笼8-氧鸟嘌呤(photocaged 8-oxoguanine)的DNA的共晶体结构 描述:包含钙离子、两条DNA序列,分别为5'-D(*AP*(8OG)P*GP*TP*CP*TP*AP*C)-3' 与 5'-D(P*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*G)-3'…… 作者:Imura T、Yang K.-C、Hosokawa Y、Shih H.-Y、Ban Y、Yamamoto J、Maestre-Reyna M. 提交日期:2024-11-14 发布日期:2025-07-23 最后修改日期:2025-09-10 实验方法:X射线衍射(X-RAY DIFFRACTION),分辨率2.81埃(Å) 引用文献:《重新审视携带光笼底物的DNA糖苷酶共晶体结构:一种适宜的时间分辨晶体学研究靶点?》,刊载于《Iucrj》第12卷,2025年



