Although classical single cell RNA analysis is a very powerful tool, it nevertheless has several drawbacks. To overcome these two disadvantages, the cell hashing technique seems interesting. In this w

NIAID Data Ecosystem10

RNA sequestration in P-bodies sustains myeloid leukaemia

急性髓系白血病

P-bodyRNA隔离

Post-transcriptional mechanisms are fundamental safeguards of progenitor cell identity and are often dysregulated in cancer. Here, we identified regulators of P-bodies as crucial vulnerabilities in ac

NIAID Data Ecosystem00

Clinical and molecular characteristics of the 70 patients with AML at diagnosis included in the study.

急性髓系白血病

肿瘤基因组学

Clinical and molecular characteristics of the 70 patients with AML at diagnosis included in the study.

Figshare2015-12-02 更新10

LIN28B promotes differentiation of fully transformed AML cells but is LIN28B promotes differentiation of fully transformed AML cells but is dispensable for fetal leukemia suppression

急性髓系白血病

LIN28B

MLL-AF9 driven AML cells regress when LIN28B is ectopically expressed.RNA-seq was performed to measure LIN28B expression and associated changes in gene expression MLL-AF9 virus was used to induce AML

NIAID Data Ecosystem00

pediatric AML and normal bone marrow

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