High resolution crystal structure of rat long chain hydroxy acid oxidase in complex with the inhibitor 4-carboxy-5-[(4-chiorophenyl)sulfanyl]-1, 2, 3-thiadiazole.

High resolution crystal structure of rat long chain hydroxy acid oxidase in complex with the inhibitor 4-carboxy-5-[(4-chiorophenyl)sulfanyl]-1, 2, 3-thiadiazole. Descriptor: 5-[(4-methylphenyl)sulfanyl]-1,2,3-thiadiazole-4-carboxylic acid, FLAVIN MONONUCLEOTIDE, Hydroxyacid oxidase 2 Authors: Chen, Z, Vignaud, C, Jaafar, A, Gueritte, F, Guenard, D, Lederer, F, Mathews, F.S. Deposit date: 2011-06-15 Release date: 2012-03-07 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.35 Å) Cite: High resolution crystal structure of rat long chain hydroxy acid oxidase in complex with the inhibitor 4-carboxy-5-[(4-chlorophenyl)sulfanyl]-1, 2, 3-thiadiazole. Implications for inhibitor specificity and drug design. Biochimie, 94, 2012

本数据集包含大鼠长链羟酸氧化酶与抑制剂4-羧基-5-[(4-氯苯基)硫基]-1,2,3-噻二唑结合的高分辨率晶体结构。描述符：5-[(4-甲基苯基)硫基]-1,2,3-噻二唑-4-羧酸、黄素单核苷酸（FLAVIN MONONUCLEOTIDE）、羟酸氧化酶2（Hydroxyacid oxidase 2）。作者：Chen, Z、Vignaud, C、Jaafar, A、Gueritte, F、Guenard, D、Lederer, F、Mathews, F.S.。沉积日期：2011-06-15；发布日期：2012-03-07；最后修改日期：2023-09-13。实验方法：X射线衍射（X-RAY DIFFRACTION），分辨率为1.35埃（Å）。引用文献：《大鼠长链羟酸氧化酶与抑制剂4-羧基-5-[(4-氯苯基)硫基]-1,2,3-噻二唑结合的高分辨率晶体结构：抑制剂特异性与药物设计的启示》，刊载于《Biochimie》第94卷，2012年。