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An antibody from single human VH-rearranging mouse neutralizes all SARS-CoV-2 variants through BA.5 by inhibiting membrane fusion

NIAID Data Ecosystem2026-05-02 收录

新冠病毒中和抗体

膜融合抑制剂

数据链接：

https://www.rcsb.org/structure/7UPY 数据链接链接失效反馈

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资源简介：

An antibody from single human VH-rearranging mouse neutralizes all SARS-CoV-2 variants through BA.5 by inhibiting membrane fusion

应用场景：

创建时间：

2024-11-20

膜融合抑制剂

抗新冠病毒药物设计

The pandemic of acute respiratory disease in 2019 caused by highly pathogenic and infectious SARS-CoV-2 has seriously endangered human public safety. The 6-HB (HR1–HR2 complex) formation occurring in

NIAID Data Ecosystem50

SARS-CoV-2 S trimer with one RBD in the open state and complexed with one H014 Fab.

结构生物学

新冠病毒中和抗体

SARS-CoV-2 S trimer with one RBD in the open state and complexed with one H014 Fab. Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-d

Protein Data Bank Japan2024-10-09 更新30

Cross-Neutralization of Emerging SARS-CoV-2 Variants

新冠病毒中和抗体

病毒变异免疫应答

To address the specific antibody targets that were affected by recent SARS-CoV-2 variants, we generated 43 monoclonal antibodies (mAbs) from 10 convalescent donors that bound three distinct domains of

Immunology Database and Analysis Portal2025-10-30 更新20

SARS-CoV-2 spike in complex with the S2K146 neutralizing antibody Fab fragment (two receptor-binding domains open)

抗原抗体复合物结构

新冠病毒中和抗体

SARS-CoV-2 spike in complex with the S2K146 neutralizing antibody Fab fragment (two receptor-binding domains open)

NIAID Data Ecosystem30

Crystal structure of SARS-CoV-2 spike receptor-binding domain (Delta) in complex with pH-dependent nanobody MNb-11.

抗原抗体复合物结构

新冠病毒中和抗体

Crystal structure of SARS-CoV-2 spike receptor-binding domain (Delta) in complex with pH-dependent nanobody MNb-11.

NIAID Data Ecosystem30