In developing mammalian kidney, nephron progenitor cells (NPC) give rise to all cells in mature nephrons. Several transcription factors, including Six2, Hoxd11, Osr1 and Wt1, are expressed in NPC and

NIAID Data Ecosystem20

Table2_Characterization of the microRNA Expression Profiles in the Goat Kid Liver.DOCX

器官发育调控

miRNA表达谱分析

The liver is the largest digestive gland in goats with an important role in early metabolic function development. MicroRNAs (miRNA) are crucial for regulating the development and metabolism in the goa

NIAID Data Ecosystem20

A Secreted BMP Antagonist, Cer1, Fine Tunes the Spatial Organization of the Ureteric Bud Tree during Mouse Kidney Development

器官发育调控

输尿管芽分支模式

The epithelial ureteric bud is critical for mammalian kidney development as it generates the ureter and the collecting duct system that induces nephrogenesis in dicrete locations in the kidney mesench

NIAID Data Ecosystem30

Gain-of-function ENL YEATS domain mutations impede nephrogenesis through gene expression control [RNA-seq]

器官发育调控

癌症分子机制

Hotspot gain-of-function mutations in the YEATS domain of the histone reader protein ENL have been identified in Wilms’ tumor. To investigate the pathogenic role of these cancer-associated ENL mutatio

NIAID Data Ecosystem20

The sexual identity of adult intestinal stem cells controls organ size and plasticity.

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