RNAseq analysis for transcriptomes of ATO treated U937 cell lines expressing p53-R280I or p53 wild-type
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https://www.ncbi.nlm.nih.gov/sra/SRP398071
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资源简介:
To globally evaluate to what extend the p53 mutant transcription activity can be restored by arsenic trioxide (ATO), p53-null U937 cells introduced with p53-R280I or wild-type p53 were treated with or without 1 µg/mL ATO. mRNA was isolated and then subject to deep sequencing, using Illumina HiSeq. The sequence reads that passed quality filters were analyzed using Cutadapt. Overall design: RNAseq to evaluate mutant p53 transcriptional activity upon ATO treatment.
创建时间:
2024-08-01



