SARS-CoV-2 RNA in blood

This dataset provides supplementary material for a report of the prevalence of SARS-CoV-2 RNA in blood and blood products.<br> <b>Extended Data File 1: Metadata table providing data for prevalence of SARS-CoV-2 RNA in blood and blood products based on a systematic literature review. </b>Details of 28 citations are presented, and the 22 studies included in quantitative meta-analysis are indicated.<br> <b>Extended Data File 2: qRT-PCR quantification of vRNA from sera and viral culture assays.</b> Calculation of vRNA copy numbers, and qRT-PCR results in figure and table format.<br> <b>Underlying Data File 1: Metadata table providing underlying data for serum samples from adults with confirmed SARS-CoV-2 infection, based on RT-PCR nose/throat swab. </b>Sheet 1: samples obtained through patients recruited into a UK clinical cohort at Oxford University Hospitals NHS Foundation Trust (n=212 samples from 167 unique individuals). Cells highlighted in blue show follow-up samples collected from the same individual at different time points. Cells highlighted in orange show serum PCR positives. Sheet 2: samples obtained from convalescent donors a minimum of 28 days post resolution of symptoms, via NHS Blood and Transplant, NHSBT (n=142 samples from 142 individuals).<br><b>RT-PCR Primer sequences: </b>provided in a .xlsx file.<br><b> </b><b>PRISMA checklist: </b>reporting for systematic review and meta-analysis<br><b> </b><b>STROBE checklist: </b>reporting for cohort studies

本数据集为《血液及血液制品中SARS-CoV-2 RNA流行情况报告》提供补充资料。
**扩展数据文件1：元数据表，基于系统文献综述，收录血液及血液制品中SARS-CoV-2 RNA流行情况相关数据**。共收录28篇引文的详细信息，并标注出纳入定量荟萃分析的22项研究。
**扩展数据文件2：血清病毒RNA（viral RNA, vRNA）的实时荧光定量逆转录聚合酶链反应（quantitative real-time reverse transcription polymerase chain reaction, qRT-PCR）定量检测及病毒培养实验数据**。包含病毒RNA拷贝数计算结果，以及以图表与表格形式呈现的qRT-PCR检测结果。
**基础数据文件1：元数据表，基于逆转录聚合酶链反应（reverse transcription polymerase chain reaction, RT-PCR）鼻咽拭子检测结果，收录确诊SARS-CoV-2感染成人血清样本的原始数据**。
表1：样本取自英国牛津大学医院国民保健服务基金会信托基金（Oxford University Hospitals NHS Foundation Trust）招募的临床队列受试者，共纳入167名独立个体的212份血清样本。其中蓝色高亮单元格代表从同一受试者不同时间点采集的随访样本，橙色高亮单元格代表血清PCR检测呈阳性的样本。
表2：样本取自英国国民保健署血液与移植中心（NHS Blood and Transplant, NHSBT）招募的症状缓解至少28天的康复献血者，共纳入142名个体的142份血清样本。
**RT-PCR引物序列：以.xlsx格式文件提供**。
**PRISMA检查表：系统综述与荟萃分析报告规范**
**STROBE检查表：队列研究报告规范**