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Identification of MEIS2 binding sites through ChIP-seq in the neuroblastoma Kelly and BE(2)-C cell lines.

ChEBI2022-04-14 更新2026-07-12 收录

神经母细胞瘤转录调控

ChIP-seq蛋白质结合位点

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-MTAB-10620 数据链接链接失效反馈

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资源简介：

Identification of MEIS2 binding sites through ChIP-seq in the neuroblastoma Kelly and BE(2)-C cell lines.

应用场景：

创建时间：

2022-04-14

神经母细胞瘤转录调控

MYCN增强子结合

In neuroblastoma, amplification of the oncogenic basic helix-loop-helix (bHLH) transcription factor (TF) MYCN is the defining prognosticator of high-risk disease, occurs in one-third of neuroblastoma,

NIAID Data Ecosystem90

Enhancer invasion shapes MYCN dependent transcriptional amplification in neuroblastoma [ATAC-seq]. Homo sapiens

神经母细胞瘤转录调控

MYCN扩增研究

NIAID Data Ecosystem60

TCF4 is a key mediator of cell identity in neuroblastoma and vulnerable to protein degradation by multiple epigenetic factors [RNA-seq]

神经母细胞瘤转录调控

疾病靶点发现

Neuroblastomas (NBs) are aggressive pediatric tumors that are responsible for up to 15% of all pediatric cancer deaths. Two differentiation states exist in NB tumors, a majority of more committed ADRN

NIAID Data Ecosystem20

Enhancer invasion shapes MYCN dependent transcriptional amplification in neuroblastoma [ATAC-seq]

神经母细胞瘤转录调控

MYCN扩增研究

NIAID Data Ecosystem70

Genome-wide chromatin-immunoprecipitation studies for ISL1 in SH-SY5Y neuroblastoma cell line. Homo sapiens

神经母细胞瘤转录调控

功能基因组学

The LIM-homeodomain transcription factor ISL1 plays an essential role in sympathetic neuronogenesis. Expression of ISL1 has been associated with neuroblastoma, a pediatric tumor derived from sympatho-

NIAID Data Ecosystem50

Identification of MEIS2 binding sites through ChIP-seq in the neuroblastoma Kelly and BE(2)-C cell lines.

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