Crystal Structure of Broadly Neutralizing Antibody 3I14 Bound to the Influenza A H3 Hemagglutinin

Crystal Structure of Broadly Neutralizing Antibody 3I14 Bound to the Influenza A H3 Hemagglutinin Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Harshbarger, W.D, Lockbaum, G.J, Deming, D.T, Attatippaholkun, N, Schiffer, C.A, Marasco, W.A. Deposit date: 2020-04-03 Release date: 2020-11-25 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (3.46 Å) Cite: Unique structural solution from a V H 3-30 antibody targeting the hemagglutinin stem of influenza A viruses. Nat Commun, 12, 2021

广谱中和抗体3I14与甲型H3血凝素结合的晶体结构 数据集描述：2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖（2-acetamido-2-deoxy-beta-D-glucopyranose）-(1→4)-2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖（2-acetamido-2-deoxy-beta-D-glucopyranose）、血凝素（Hemagglutinin）、β-D-吡喃甘露糖（beta-D-mannopyranose）-(1→4)-2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖（2-acetamido-2-deoxy-beta-D-glucopyranose）-(1→4)-2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖（2-acetamido-2-deoxy-beta-D-glucopyranose）等；作者：Harshbarger, W.D.、Lockbaum, G.J.、Deming, D.T.、Attatippaholkun, N.、Schiffer, C.A.、Marasco, W.A.；提交日期：2020-04-03；发布日期：2020-11-25；最后修改日期：2024-11-06；方法：X射线衍射（X-RAY DIFFRACTION），分辨率3.46埃；引用文献：靶向甲型流感病毒血凝素茎区的VH3-30抗体独特结构解析，《自然-通讯》，12卷，2021年