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Cryo-EM structure of the c-di-GMP-bound FleQ-FleN master regulator complex from Pseudomonas aeruginosa

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Protein Data Bank Japan2025-10-01 更新2026-06-30 收录
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Cryo-EM structure of the c-di-GMP-bound FleQ-FleN master regulator complex from Pseudomonas aeruginosa Descriptor: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), Antiactivator FleN, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... Authors: Torres-Sanchez, L.T, Krasteva, P.V. Deposit date: 2023-06-08 Release date: 2023-12-13 Last modified: 2025-10-01 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Structures of the P. aeruginosa FleQ-FleN master regulators reveal large-scale conformational switching in motility and biofilm control. Proc.Natl.Acad.Sci.USA, 120, 2023
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2023-06-08
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