Actual vs Expected Reductions in Systolic Blood Pressure and LDL-cholesterol in Trials of ‘Polypills’.
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*rounded to nearest 10 mm Hg;
**based on mean baseline SBP & standard dose equivalence (from Law 2009) [4];
∧mean baseline LDL × percentage reduction in LDL cholesterol for the statin at that dose (from Law 2003) [5]
#estimate: two drugs at half dose therefore an overestimate of likely effect;
##estimate: two drugs at half dose therefore an underestimate of likely effect; 12.7 mmHg for two drugs at standard dose;
βestimate: three drugs at standard dose; 15.2 mmHg for three drugs at half standard dose.
创建时间:
2012-12-19



