Additional file 1 of Elevated levels of butyric acid in the jejunum of an animal model of broiler chickens: from early onset of Clostridium perfringens infection to clinical disease of necrotic enteritis

Supplementary Material 1: Table S1 Composition of feed used in the study. Table S2 Metabolite ratios determined across different NE birds. Table S3 34 differentially expressed metabolites across different NE categories of birds versus healthy control birds. Table S4 Logistic regression analysis of key metabolites identified in Clostridium perfringens infected birds. Table S5 Pathway analysis of 34 metabolites identified in NE birds. Table S6 Metabolite-protein interaction network analysis of 34 jejunal metabolites exposed to CP infection. Table S7 Metabolite ratios determined across different NE birds challenged with CP with different toxin gene numbers. Table S8 Comparative analysis of 21 metabolites in broiler chickens infected with CP isolates with different gene combinations (2T, 3T, 4T and combined). Table S9 Logistic regression analysis of key metabolites identified in Clostridium perfringens infected birds. Table S10 Pathway analysis of 21 jejunal metabolites identified in NE birds treated with CP isolates with toxin genes combinations. Table S11 Metabolite-protein interaction network analysis of 21 jejunal metabolites exposed to CP infection with different toxin gene combinations.