Clonorchis sinensis-Excretory/Secretory Proteins ameliorates Inflammation in Rheumatoid Arthritis and Ankylosing Spondylitis

We aimed to investigate whether substances secreted by Clonorchis sinensis-Excretory/Secretory protein (CS-ESP), rather than direct contact with crude proteins, have an effect on the inflammation of rheumatoid arthritis (RA) and ankylosing spondylitis (AS), and to identify specific peptides through related proteomic analysis to determine which proteins exhibit anti-inflammatory effects more specifically.