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DNA methyation of intragenic CpG islands are required for differentiation from iPSC to NPC

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NIAID Data Ecosystem2026-03-12 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP278588
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We generated whole genome bisulfite sequencing (WGBS) data with high sequencing depth in induced pluripotent stem cell (iPSC), neuronal progentior cell (NPC) and Early Neuron (EN), and investigated the relationship between DNA methylation changes in CpG islands (CGIs) and corresponding gene expression during NPC differentiation Overall design: WGBS for iPSC, NPC and EN. mRNA-seq for iPSC and NPC. H3K4me3 ChIP-seq for iPSC and NPC. H3K27me3 ChIP-seq for iPSC and NPC
创建时间:
2021-01-11
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