Perinatal smoke/nicotine exposure alters lung development and causes asthma in exposed offspring, transmitted transgenerationally. The mechanism underlying the transgenerational inheritance of perinat
SH-SY5Y and HK-2 cells were exposed to citrinin (CIT) for 24 hours. Cell viability of cell lines were assessed via MTT test. 5-methylcytosine levels and expression profiles of genes involved in DNA me
Rationale: Methamphetamine (METH) exposure has toxicity in sperm epigenetic phenotype, and increase the risk for developing addiction in their offspring. However, the underlying transgeneration
We exposed dams to rotenone starting 2 weeks prior to conception all the way to the end of lactation to determine its effects on the DNA methylation landscape of the offspring. We find that this treat