HDAC inhibitor PCI-24781 inhibits metastasis in breast cancer

RNA-seq analysis was performed to identify key signaling responding to PCI-24781 in MDA-MB-231 Overall design: Four independent sample groups were exposed to PCI-24781 and controls were treated with DMSO for 24 h and 48 h (DMSO-treated groups: DMSO 24 h, DMSO 48 h; PCI-24781-treated groups: 100 nM 24 h; 100 nM 48 h; 200 nM 24 h; 200 nM 48 h) in MDA-MB-231 and were analyzed through RNA-seq.