THYMIDYLATE SYNTHASE R178T, R179T DOUBLE MUTANT

THYMIDYLATE SYNTHASE R178T, R179T DOUBLE MUTANT Descriptor: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, POTASSIUM ION, PROTEIN (THYMIDYLATE SYNTHASE) Authors: Morse, R.J, Finer-Moore, J.S, Stroud, R.M. Deposit date: 1998-08-11 Release date: 1998-08-19 Last modified: 2023-08-09 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Energetic contributions of four arginines to phosphate-binding in thymidylate synthase are more than additive and depend on optimization of "effective charge balance". Biochemistry, 39, 2000胸苷酸合酶（thymidylate synthase）R178T、R179T双突变体 描述符：2'-脱氧尿苷5'-单磷酸、钾离子、蛋白质（胸苷酸合酶） 作者：Morse, R.J.、Finer-Moore, J.S.、Stroud, R.M. 存入日期：1998-08-11 发布日期：1998-08-19 最后修改日期：2023-08-09 实验方法：X射线衍射（2.4 Å） 引用文献：《四个精氨酸残基对胸苷酸合酶磷酸结合的能量贡献远超加和性且依赖"有效电荷平衡"的优化》，《生物化学（Biochemistry）》，第39卷，2000年