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Inhibition of fusidic acid resistance through restricting conformational flexibility in domain III of EF-G

NIAID Data Ecosystem2026-05-10 收录

细菌耐药性机制

构象动力学

数据链接：

https://www.omicsdi.org/dataset/pride/PXD062993 数据链接链接失效反馈

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资源简介：

HDX-MS was used to study the binding of FusB to EF-G variants.

应用场景：

创建时间：

2025-12-15

细菌耐药性机制

细菌转录组学

RNA-Seq on common bacterial pathogens in the presence vs absence of a variety of antibiotics. Two susceptible and two resistant isolates were exposed to antibiotics in laboratory culture, total RNA wa

NIAID Data Ecosystem40

Pairwise distance in Å between catalytic residues in Class A β-lactamases – Ser70(a), Lys73(b), Ser130(c), [Arg/Lys]234(d), Glu166(e).

β-内酰胺酶催化残基距离

细菌耐药性机制

Pairwise distance in Å between catalytic residues in Class A β-lactamases – Ser70(a), Lys73(b), Ser130(c), [Arg/Lys]234(d), Glu166(e).

NIAID Data Ecosystem10

aANM data for the transition of a GroEL subunit between R�� and T forms(*).

构象动力学

结构生物学

(*)mT(k) and mR��(k) are the number of modes recruited at step k, starting from the respective states R�� and T; RMSD values are calculated using Eq. (3). A and B designate the respective states T and

Figshare2015-12-02 更新00

Exogenous pyruvate promotes gentamicin uptake to kill antibiotic-resistant Vibrio alginolyticus

细菌耐药性机制

细菌代谢干预治疗

Exogenous pyruvate promotes gentamicin uptake to kill antibiotic-resistant Vibrio alginolyticus

integrated proteome resources30

Chemogenomic screen for imipenem resistance in Gram-negative bacteria (WT)

细菌耐药性机制

化学基因组学

Carbapenem-resistant Gram-negative bacteria are considered as a major threat to global health. Imipenem (IMP) is used as a last line of treatment against these pathogens but its efficiency is diminish

NIAID Data Ecosystem00

Inhibition of fusidic acid resistance through restricting conformational flexibility in domain III of EF-G

资源简介：

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