Minimal critical region (MCR) in choriocarcinomas.

(1)The localization of MCRs with a contribution of de novo choriocarcinomas are indicated in bold. (2)BeWo = A, JAR = B, JEG = C. (3)The genes that meet the selection criteria and were selected are indicated in bold characters. The genes subject to parental imprinting are underlined : (m) = maternal imprinted gene; (p) = paternal imprinted gene. The genes that does not meet the selection criteria but are of interest for various reasons are indicated in plain characters. (4)BeWo and JEG are included for simplicity although they don't define a real MCR. (5)indicate the “wave-crest” amplification of the JAR cell line probably the site of chromothripsis phenomenon [45]. A basal gain under it was observed between 12pter and 12q21.3. (6)JAR contribute for only mir 371 372 & 373.