首页/数据集/Siglec-9 acts as an immune checkpoint molecule on macrophages in glioblastoma, restricting T cell priming and immunotherapy response

Siglec-9 acts as an immune checkpoint molecule on macrophages in glioblastoma, restricting T cell priming and immunotherapy response

NIAID Data Ecosystem2026-05-01 收录

母细胞瘤免疫微环境

Siglec-9免疫检查点

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE235913 数据链接链接失效反馈

官方服务：

资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

应用场景：

创建时间：

2023-09-28

母细胞瘤免疫微环境

肿瘤相关巨噬细胞

Glioblastoma is a highly malignant and incurable brain tumor characterized by intrinsic and adaptive resistance to immunotherapies. However, how glioma cells induce tumor immunosuppression and escape

NIAID Data Ecosystem60

CD169 is a marker of IFN-γ-stimulated inflammatory macrophages in brain tumor [WG vs TG]. CD169 is a marker of IFN-γ-stimulated inflammatory macrophages in brain tumor [WG vs TG]

母细胞瘤免疫微环境

单细胞转录组学

Therapies against glioblastoma multiforme (GBM) have been largely ineffective due to the infiltration of immunosuppressive tumor-associated macrophages (TAMs). Recent studies demonstrated that TAMs ca

NIAID Data Ecosystem40

Additional file 2 of Characterization and prognostic of CD8 + TIM3 + CD101 + T cells in glioblastoma multiforme

母细胞瘤免疫微环境

T细胞亚群预后标志物

Supplementary Material 2

Figshare2025-05-15 更新30

Tumor-associated hematopoietic stem and progenitor cells positively linked to glioblastoma progression

母细胞瘤免疫微环境

造血干细胞肿瘤关联

Brain tumors are typically immunosuppressive and refractory to immunotherapies for reasons that remain poorly understood. The unbiased profiling of immune cell types in the tumor microenvironment may

NIAID Data Ecosystem50

Table S3 from Phenotypic Mapping of Pathologic Cross-Talk between Glioblastoma and Innate Immune Cells by Synthetic Genetic Tracing

母细胞瘤免疫微环境

实验工具清单

Supplementary Table S3. List of reagents, software and deposited data

Figshare2021-03-01 更新30