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Chemical incorporation of 1-methyladenosine into oligonucleotides

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PubMed Central2002-03-01 更新2026-05-16 收录
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The base moiety of 1-N-methyladenosine can be protected with a chloroacetyl group for incorporation of this modified nucleoside into DNA and RNA. Carefully controlled anhydrous conditions are needed for deprotection of the oligonucleotides.

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2002-03-01
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